hrp0095t19 | Section | ESPE2022

Impaired gonadal function among pediatric Fanconi anemia patients following hematopoietic stem cell transplantation

Koo Jane , Rios Julie , Mehta Parinda , Davies Stella , Myers Kasiani , Howell Jonathan

Background: Gonadal dysfunction and fertility impairment are some of the many clinical manifestations described among patients with Fanconi anemia (FA). Many who receive hematopoietic stem cell transplantation (HSCT) suffer additionally from infertility due to gonadal damage from their preparative regimen. The effect of HSCT on gonadal insufficiency and fertility potential among children with FA is largely unknown.Methods:</stron...